Unique to the Cruise Line Cruises
Browse 211 unique to the cruise line cruises available now. Compare itineraries, dates, and pricing below, then reach out to a Ships and Trips Travel advisor when you're ready to book — the price is the same as booking direct, plus the personal guidance and Signature Travel Network perks that come with working with us.
Uniworld Boutique River Cruises
7-night Delightful Danube Cruise
S.S. Beatrice
From
$4,999
per person
Destination: Europe, River Cruises, Germany
Budapest/Regensburg
Uniworld Boutique River Cruises
9-night Delightful Danube & Prague Cruise/Land Package
S.S. Beatrice
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for pricing
Destination: Europe, River Cruises, Germany
Budapest/Prague
AmaWaterways
7-night Colors Of Provence With 3 Nights Paris Pre-Cruise Cruise/Land…
AmaKristina
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for pricing
Destination: Europe, River Cruises, France
Paris/Arles
AmaWaterways
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise…
AmaMelodia
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for pricing
Destination: South America, River Cruises, Small Ships
Cartagena/Barranquilla
Uniworld Boutique River Cruises
10-night Remarkable Rhine & Historic Holland Cruise
S.S. Antoinette
From
$3,499
per person
Destination: Europe, River Cruises, France
Amsterdam/Basel
AmaWaterways
7-night Wonders Of Colombia Cruise
AmaMelodia
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for pricing
Destination: South America, River Cruises, Small Ships
Cartagena/Barranquilla
Cunard®
7-night Abbey Road At Sea Cruise
Queen Mary 2®
From
$1,299
per person
Destination: Europe, Trans-Atlantic, Great Britain
London (Southampton)/New York City
Uniworld Boutique River Cruises
9-night Vienna & Capital Cities Of The Danube Cruise/Land Package
S.S. Emilie
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for pricing
Destination: Europe, River Cruises, Small Ships
Vienna/Belgrade
Uniworld Boutique River Cruises
7-night Capital Cities Of The Danube Cruise
S.S. Emilie
From
$3,999
per person
Destination: Europe, River Cruises, Small Ships
Vienna/Belgrade
AmaWaterways
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise…
AmaMagdalena
From
$4,991
per person
Destination: South America, River Cruises, Small Ships
Medellin/Cartagena
AmaWaterways
7-Night Magic of Colombia With 3 Nights In Medellín Pre Cruise And 3…
AmaMagdalena
From
$7,166
per person
Destination: South America, River Cruises, Small Ships
Medellin/Panama City
American Cruise Lines
11-night Mississippi Explorer Cruise
American Serenade
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for pricing
Destination: River Cruises, Small Ships, Mississippi River Cruise
New Orleans/Memphis
AmaWaterways
7-night Magic of Colombia Cruise
AmaMagdalena
From
$3,299
per person
Destination: South America, River Cruises, Small Ships
Barranquilla/Cartagena
AmaWaterways
7-night Magic Of Colombia With 3-nights Panama Post Cruise…
AmaMagdalena
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for pricing
Destination: South America, River Cruises, Small Ships
Barranquilla/Panama City
Seabourn
13-night Atlantic Coast: Lighthouses & New England Charms Cruise
Seabourn Ovation
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for pricing
Destination: Canada/New England, Trans-Atlantic, Canada
Montreal/Miami
Uniworld Boutique River Cruises
10-night Remarkable Rhine & Historic Holland Cruise
S.S. Antoinette
From
$3,399
per person
Destination: Europe, River Cruises, France
Basel/Amsterdam
Uniworld Boutique River Cruises
7-night Delightful Danube Cruise
S.S. Beatrice
From
$2,499
per person
Destination: Europe, River Cruises, Germany
Budapest/Regensburg
Uniworld Boutique River Cruises
9-night Delightful Danube & Prague Cruise/Land Package
S.S. Beatrice
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for pricing
Destination: Europe, River Cruises, Germany
Budapest/Prague
SeaDream Yacht Club
13-night Transatlantic Autumn Voyage I Cruise
SeaDream I
From
$5,519
per person
Destination: Caribbean, Europe, Mediterranean
Malaga/St. Maarten (Philipsburg)
PONANT EXPLORATIONS
14-night The Best Of Chilean Fjords Cruise
Le Lyrial
From
$13,070
per person
Destination: South America, Antarctica, Small Ships
Santiago (Valparaiso)/Ushuaia
Windstar Cruises
8-night 2026 Spanish Mystery Cruise
Star Legend
From
$2,982
per person
Destination: Europe, Mediterranean, Small Ships
Barcelona/Malaga
Oceania Cruises
10-night Radiant Rivieras Voyage
Oceania Marina
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for pricing
Destination: Europe, Mediterranean, Italy
Barcelona/Rome (Civitavecchia)
Aqua Expeditions
7-night Amazon Expeditions Cruise
Aqua Nera
Contact Advisor
for pricing
Destination: South America, Small Ships, Peru
Roundtrip Iquitos
Windstar Cruises
14-night Knot Your Average Crossing Cruise
Wind Star
From
$3,622
per person
Destination: Caribbean, Europe, Trans-Atlantic
Lisbon/Bridgetown (Barbados)