Mississippi River Cruise

Mississippi River Cruise

About Mississippi River Cruise

Mississippi River Cruise

Quick Facts

event Best Time to Visit The best time to visit is in spring or fall, when temperatures are mild and river levels are optimal for cruising.
directions_boat Cruise Options 569 available

The Mississippi River Cruise offers a unique blend of history, culture, and natural beauty, providing travelers with a distinctive way to explore America's heartland. This iconic waterway, the second-longest river in the United States, flows over 2,300 miles, weaving through ten states and offering a front-row seat to the diverse landscapes of the American Midwest and South. Passengers can step back in time aboard a classic steamboat replica, complete with elegant dining and period furnishings. Along the journey, cruisers will experience charming riverside towns, such as Hannibal, Missouri, the boyhood home of Mark Twain, and Natchez, Mississippi, known for its antebellum architecture. The cruise offers enriching onboard lectures, themed entertainment, and regional cuisine, making it a cultural and educational experience. From the vibrant music scene of New Orleans to the historic battlegrounds of Vicksburg, each stop provides a unique glimpse into American history and culture.

Highlights

  • Explore the historic streets and antebellum homes of Natchez, Mississippi.
  • Discover the musical heritage of New Orleans' French Quarter.
  • Visit Mark Twain's childhood home in Hannibal, Missouri.
  • Experience the Civil War history at the Vicksburg National Military Park.
  • Enjoy regional cuisine and live jazz performances onboard the steamboat.

Tours to Mississippi River Cruise

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Cruises to Mississippi River Cruise

Viking Mississippi
Viking

7-night Mississippi Delta Explorer Cruise

Viking Mississippi
From $6,799 per person
Departure: Sep 19, 2026
Length: 7 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
New Orleans/Memphis
American Splendor
American Cruise Lines

11-night Smoky Mountains National Park Cruise/Land Package

American Splendor
Contact Advisor for pricing
Departure: Sep 22, 2026
Length: 11 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
Nashville/Knoxville
American Splendor
American Cruise Lines

8-night Tennessee Rivers Cruise

American Splendor
Contact Advisor for pricing
Departure: Sep 22, 2026
Length: 8 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
Nashville/Chattanooga
American Serenade
American Cruise Lines

15-night Grand Heartland Cruise

American Serenade
Contact Advisor for pricing
Departure: Sep 25, 2026
Length: 15 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
St. Paul/New Orleans
American Melody
American Cruise Lines

8-night Upper Mississippi River Cruise

American Melody
Contact Advisor for pricing
Departure: Sep 25, 2026
Length: 8 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
St. Louis, MO/St. Paul, MN
American Heritage
American Cruise Lines

8-night Lower Mississippi River Cruise

American Heritage
Contact Advisor for pricing
Departure: Sep 25, 2026
Length: 8 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
New Orleans/Memphis

View all 569 cruises to Mississippi River Cruise