American Cruise Lines
American Cruise Lines operates a fleet of small, U.S.-flagged ships built specifically for domestic river and coastal itineraries, including the Mississippi, Columbia and Snake Rivers, and New England and the Pacific Northwest. Every voyage sails entirely within the United States, with an all-American crew and no international ports of call.
Cruises with American Cruise Lines
American Cruise Lines
8-night Hudson River Fall Foliage 2026 Cruise
American Legend
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Destination: Small Ships, New York City, Hudson River Cruise
Albany, NY/New York City
American Cruise Lines
8-night Northeast Harbors Cruise
American Maverick
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Destination: Canada/New England, Small Ships, New York City
Boston/New York City
American Cruise Lines
8-night Chesapeake Bay Cruise
American Independence
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Destination: River Cruises, Small Ships, USA Cruises
Roundtrip Baltimore, MD
American Cruise Lines
8-night Upper Mississippi River Cruise
American Melody
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Destination: River Cruises, Small Ships, Mississippi River Cruise
St. Louis, MO/St. Paul, MN
American Cruise Lines
8-night Columbia and Snake Rivers Cruise
American Harmony
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Destination: River Cruises, Small Ships, Pacific Northwest
Portland, OR/Clarkston, WA
American Cruise Lines
8-night Columbia and Snake Rivers Cruise
American Jazz
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Destination: River Cruises, Small Ships, Pacific Northwest
Clarkston/Portland
American Cruise Lines
7-night Highlights of the Mississippi Cruise
American Serenade
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Destination: River Cruises, Small Ships, Mississippi River Cruise
Roundtrip New Orleans
American Cruise Lines
8-night Hudson River Fall Foliage 2026 Cruise
American Ranger
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for pricing
Destination: River Cruises, Small Ships, New York City
Albany, NY/New York City