American Serenade

American Cruise Lines · View Fleet

American Serenade
American Serenade won Cruise Critic’s Editors’ Picks Award for Best New River Cruise Ship of the Year recently, the first time an American ship has received this prestigious award. Introduces an updated modern interior design, integrating an elegant and refined aesthetic with tradition for the spacious comfort found aboard all of ships Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.

Sample Cruises on American Serenade

American Serenade
American Cruise Lines

8-night Arkansas River Cruise

American Serenade
Contact Advisor for pricing
Departure: Nov 8, 2026
Length: 8 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
Little Rock/Tulsa
American Serenade
American Cruise Lines

8-night Arkansas River Cruise

American Serenade
Contact Advisor for pricing
Departure: Nov 15, 2026
Length: 8 nights
Destination: River Cruises, Small Ships, Mississippi River Cruise
Tulsa/Little Rock
American Serenade
American Cruise Lines

7-night Gulf Coast Cruise

American Serenade
Contact Advisor for pricing
Departure: Dec 8, 2026
Length: 7 nights
Destination: River Cruises, Small Ships, Florida
New Orleans/Pensacola
American Serenade
American Cruise Lines

7-night Gulf Coast Cruise

American Serenade
Contact Advisor for pricing
Departure: Dec 14, 2026
Length: 7 nights
Destination: River Cruises, Small Ships, Florida
Pensacola/New Orleans

Request Info

Interested in sailing on the American Serenade? A specialist will follow up with itinerary options and pricing.